国产精品自在在线香蕉-国产精品自在线拍国产-国产精品自在线拍-国产精品自在线-国产精品自在欧美一区-国产精品自线在线播放

最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁(yè)>>免疫學(xué)>>一抗>>受體蛋白酪氨酸磷酸酶F抗體
受體蛋白酪氨酸磷酸酶F抗體
  • 產(chǎn)品貨號(hào):
    BN40309R
  • 中文名稱:
    受體蛋白酪氨酸磷酸酶F抗體
  • 英文名稱:
    Rabbit anti-LAR Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號(hào)

    產(chǎn)品規(guī)格

    售價(jià)

    備注

  • BN40309R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Human(predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40309R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Human(predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱LAR
中文名稱受體蛋白酪氨酸磷酸酶F抗體
別    名LAR; LAR protein; LARFN5C; PTPRF; LARS; LCA homolog; Leukocyte antigen related (LAR) PTP receptor; Leukocyte antigen related; Leukocyte antigen related PTP receptor; Leukocyte antigen related tyrosine phosphatase; Leukocyte common antigen related; Protein Tyrosine Phosphatase Receptor Type F; Protein tyrosine phosphatase receptor type F polypeptide; Ptprf; PTPRF protein; PTPRF_HUMAN; Receptor linked protein tyrosine phosphatase LAR; Receptor type tyrosine protein phosphatase F; Receptor type tyrosine protein phosphatase F precursor; Receptor-type tyrosine-protein phosphatase F.  
研究領(lǐng)域腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量210kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PTPRF:30-100/1907 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

Function:
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity.
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.

Subunit:
Interacts with GRIP1. Interacts with PPFIA1, PPFIA2 and PPFIA3. Interacts with INSR.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Contains 8 fibronectin type-III domains.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 tyrosine-protein phosphatase domains.

SWISS:
P10586

Gene ID:
5792

Database links:

Entrez Gene: 5792 Human

Entrez Gene: 19268 Mouse

Entrez Gene: 360406 Rat

Entrez Gene: 12072 Cow

Omim: 179590 Human

SwissProt: P10586 Human

SwissProt: Q5T021 Human

SwissProt: Q5T022 Human

SwissProt: Q86WS0 Human

SwissProt: A2A8L5 Mouse

SwissProt: Q9EQ17 Mouse

SwissProt: Q64604 Rat

Unigene: 272062 Human

Unigene: 29855 Mouse

Unigene: 11386 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


主站蜘蛛池模板: 三门县| 黄梅县| 土默特右旗| 大姚县| 甘肃省| 崇左市| 象州县| 荣成市| 万山特区| 正镶白旗| 揭阳市| 东乌珠穆沁旗| 虹口区| 白城市| 顺昌县| 汉川市| 广水市| 东阿县| 芮城县| 马边| 长白| 五大连池市| 鸡西市| 兴安盟| 兴山县| 洛阳市| 门源| 八宿县| 宣恩县| 萨嘎县| 望江县| 道孚县| 耒阳市| 美姑县| 澎湖县| 都昌县| 德化县| 保亭| 尖扎县| 开封市| 阿勒泰市|